Droschl H
Angle Orthod. 1975 Jan;45(1):26-33. doi: 10.1043/0003-3219(1975)045<0026:TEOHOF>2.0.CO;2.
The effect of heavy continuous orthopedic forces was studied in three Saimiri Sciureus (squirrel) monkeys. Two additional monkeys served as controls. The maxillary sutures were investigated microscopically. In addition, the bone markers (tetracycline, Procion Red H-8 BS) served for quantitative evaluation under ultraviolet light. After two weeks slight remodeling activity could be observed. After one month a tremendous activity was found in the sutures. The width of the sutures was two to three times enlarged. The regular tissue pattern of the sutures had changed to a mixture of precollagen and collagen fibers running in all directions with plenty of active cells. In the ultraviolet light there is a take up of markers at the sutural margins. After three months of treatment though, the sutures showed a similar pattern. The three zones of the sutures began to form again; osteoblasts were attached to the sutural margins and reorganization was relatively complete.
在三只松鼠猴中研究了持续较大的矫形力的作用。另外两只猴子作为对照。对上颌缝线进行了显微镜检查。此外，骨标志物（四环素、活性艳红H-8 BS）用于在紫外线下进行定量评估。两周后可观察到轻微的重塑活动。一个月后，在缝线处发现了大量活动。缝线宽度扩大了两到三倍。缝线的规则组织模式已转变为前胶原和胶原纤维的混合物，这些纤维向各个方向延伸，并有大量活跃细胞。在紫外线下，在缝线边缘有标志物摄取。然而，治疗三个月后，缝线呈现出类似的模式。缝线的三个区域又开始形成；成骨细胞附着在缝线边缘，重组相对完成。
