O'Hagan M, Wallace S J
Department of Paediatrics, University Hospital of Wales, Cardiff, UK.
Brain Dev. 1994 Mar-Apr;16(2):165-7. doi: 10.1016/0387-7604(94)90058-2.
Two children treated for status epilepticus had low plasma phenytoin levels during enteral feeding, despite adequate oral dosage. The target range (10-20 mg/l) was achieved when feeds were stopped, or when intravenous phenytoin was used. Enteral feeding may interfere with the absorption of oral phenytoin thereby compromising seizure control.