Warembourg H, Bertrand M E, Lemaire P, Ginestet A, Carre A
Arch Mal Coeur Vaiss. 1975 Feb;68(2):135-46.
The action of the contrast material over the various contractility indices was assessed five minutes after left ventriculography. There was an increase of the contractility index in normal subjects. On the contrary, in coronary patients, the contractility function remained unchanged or was depressed, related to the presence or not, of signs of cardiac failure. Depression of the various indices was noted in subjects with primary cardiomyopathy. After recalling the mechanism of action of the contrast products on the cardiovascular haemodynamic parameters, the following practical conclusions were drawn in relation with a series of 65 cases of coronary heart disease: the late diastolic left ventricular pressure remained lower than 20 mmHg after ventriculography in the subjects with a normal ejection fraction; it incraeased between 20 and 30 mmHg in most of the subjects with an ejection fraction ranging from 0.4 and 0.6, finally it was constantly found above 35 mmHg in the subjects with severely disturbed ventricular contraction with an ejection fraction lower than 0.4. These results underline the interest of this simple test, easy to perform, consisting in measuring the left ventricular late diastolic pressure before and 5 minutes after left ventriculography.
在左心室造影后五分钟评估造影剂对各种收缩性指标的作用。正常受试者的收缩性指标有所增加。相反，在冠心病患者中，收缩功能保持不变或降低，这与是否存在心力衰竭体征有关。在原发性心肌病患者中观察到各种指标降低。在回顾造影剂对心血管血流动力学参数的作用机制后，针对65例冠心病患者得出以下实际结论：射血分数正常的受试者在心室造影后左心室舒张末期压力仍低于20 mmHg；射血分数在0.4至0.6之间的大多数受试者中，该压力在20至30 mmHg之间升高；最后，在心室收缩严重紊乱且射血分数低于0.4的受试者中，该压力持续高于35 mmHg。这些结果强调了这个简单测试的意义，该测试易于执行，包括在左心室造影前和造影后5分钟测量左心室舒张末期压力。
