与母亲使用可卡因相关的胎儿心肌钙化。

Fetal myocardial calcification associated with maternal cocaine use.

作者信息

Yap T E, Diana D, Herson V, Chameides L, Rowe J C

机构信息

Department of Pediatrics, University of Connecticut Health Center, Farmington 06030.

出版信息

Am J Perinatol. 1994 May;11(3):179-83. doi: 10.1055/s-2008-1040740.

DOI:10.1055/s-2008-1040740

PMID:8048980

Abstract

Two cases of fetal myocardial calcification confirmed postnatally are reported. In contrast to other reports, both infants survived with resolution of calcification by 6 and 12 months. Diagnostic investigations failed to confirm the presence of congenital infection. Both pregnancies were complicated by early cocaine use leading to the speculation that myocardial necrosis with subsequent calcification related to the toxic and/or vascular effects of cocaine was responsible. The finding of fetal myocardial calcification on prenatal ultrasound should prompt a search for causes, which may include cocaine exposure.

摘要

报告了两例出生后确诊的胎儿心肌钙化病例。与其他报告不同的是，两名婴儿均存活，钙化在6个月和12个月时消失。诊断性检查未能证实存在先天性感染。两次妊娠均因早期使用可卡因而复杂化，这引发了一种推测，即与可卡因的毒性和/或血管效应相关的心肌坏死及随后的钙化是病因。产前超声检查发现胎儿心肌钙化应促使寻找病因，其中可能包括可卡因暴露。