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透析患者心脏手术的早期及长期结果

Early and long-term results of cardiac surgery in dialysis patients.

作者信息

Blum U, Skupin M, Wagner R, Matheis G, Oppermann F, Satter P

机构信息

Department of Thoracic and Cardiovascular Surgery, University Hospital Frankfurt-am-Main, Germany.

出版信息

Cardiovasc Surg. 1994 Feb;2(1):97-100.

PMID:8049936
Abstract

Cardiac surgery in patients receiving dialysis has a high mortality and morbidity. Early long-term results have been analysed following various cardiac operative procedures. Between 1981 and 1992, 40 patients, of mean age 55.7 (range 31-71) years underwent cardiac surgery. Procedures included coronary artery bypass grafting (20 patients), aortic valve replacement (six), mitral valve replacement (four), aortic valve or mitral valve plus coronary artery bypass grafting (one each), aortic plus mitral valves (two), heart and renal transplantation (one each), atrial septal defect closure (one) and pericardial decortication (three). Before surgery, patients were in the New York Heart Association (NYHA) classes II (5%), III (52.2%) and IV (42.5%). The operative mortality rate was 15%; survivors were in NYHA classes I (3%), II (88.2%) and III (8.8%). There were 11 late deaths. Follow-up at a mean of 35 (range 1-93) months showed actuarial survival rates of 91% (1 year) and 69% (5 years). After coronary artery bypass grafting, survival rates were 95% (1 year) and 72% (5 years). Survivors were in NYHA classes I (4.7%), II (85.5%) and III (9.5%). Cardiac surgery in dialysis patients is associated with an acceptable hospital mortality; quality of life in long-term survivors is increased. Hence, surgical treatment is advocated in patients with symptomatic heart disease. Early diagnosis and surgical intervention in NYHA class II patients may lead to a lower perioperative mortality.

摘要

接受透析治疗的患者进行心脏手术,其死亡率和发病率都很高。对各种心脏手术操作后的早期长期结果进行了分析。1981年至1992年间,40例平均年龄55.7岁(范围31 - 71岁)的患者接受了心脏手术。手术包括冠状动脉旁路移植术(20例)、主动脉瓣置换术(6例)、二尖瓣置换术(4例)、主动脉瓣或二尖瓣置换加冠状动脉旁路移植术(各1例)、主动脉瓣加二尖瓣置换术(2例)、心脏和肾移植(各1例)、房间隔缺损修补术(1例)和心包剥脱术(3例)。手术前,患者的心功能分级为纽约心脏协会(NYHA)Ⅱ级(5%)、Ⅲ级(52.2%)和Ⅳ级(42.5%)。手术死亡率为15%;存活者的心功能分级为NYHAⅠ级(3%)、Ⅱ级(88.2%)和Ⅲ级(8.8%)。有11例晚期死亡。平均随访35个月(范围1 - 93个月)显示,精算生存率为1年91%、5年69%。冠状动脉旁路移植术后,生存率为1年95%、5年72%。存活者的心功能分级为NYHAⅠ级(4.7%)、Ⅱ级(85.5%)和Ⅲ级(9.5%)。透析患者的心脏手术与可接受的医院死亡率相关;长期存活者的生活质量有所提高。因此,对于有症状性心脏病的患者,提倡进行手术治疗。对NYHAⅡ级患者进行早期诊断和手术干预可能会降低围手术期死亡率。

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