Henneking K, Müller C, Franke F, Becker H, Schwemmle K
Klinik für Allgemein- und Thoraxchirurgie, Justus-Liebig-Universität Giessen.
Chirurg. 1994 May;65(5):457-68.
Children and adolescents, who received an autologous reimplant of the spleen because of traumatic injury between 1979 and 1986 were matched to a cohort of patients, splenectomized because of traumatic injury of the spleen as well and to a control group of healthy age matched individuals. In addition to a physical check-up, markers of humoral and cellular immunity (e.g. lymphocyte subpopulations and phagocytosis of pneumococcy) as well as the coagulatory and fibrinolytic system were examined. All parameters tested, were found to between results from splenectomized and healthy individuals. Our studies stress the fundamental ability of autologous spleen transplants to take over part of the splenic function on the basis of a largerly histomorphologic restitution. Thus autologous reimplantation of the spleen in children and adolescents is an excellent choice as compared to otherwise necessary splenectomy, if preservation of the organ is impossible.
1979年至1986年间因创伤性损伤接受自体脾再植入的儿童和青少年,与同样因脾创伤性损伤而接受脾切除术的一组患者以及年龄匹配的健康对照组进行了匹配。除了体格检查外,还检测了体液和细胞免疫标志物(如淋巴细胞亚群和肺炎球菌吞噬作用)以及凝血和纤维蛋白溶解系统。所有测试参数均介于脾切除患者和健康个体的结果之间。我们的研究强调了自体脾移植在很大程度上基于组织形态学恢复来接管部分脾功能的基本能力。因此,与在无法保留脾脏时进行其他必要的脾切除术相比,儿童和青少年自体脾再植入是一个很好的选择。