Gasińska T, Nowak S
I Klinika Chorób Wewnetrznych Slaskiej AM, Katowicach.
Endokrynol Pol. 1993;44(1):37-46.
Relation between the appearance of impaired carbohydrate tolerance and such factors as the duration of hyperthyroidism, age of patients, blood serum concentrations of thyroxine, triiodothyronine and free fatty acids, as well as insulin secretion both basal and stimulated by oral and "intravenous glucose administration was studied in 62 patients with untreated hyperthyroidism. Control group consisted of 24 healthy subjects having performed oral and intravenous glucose tolerance tests. Among the studied factors, high blood serum concentrations of thyroxine and triiodothyronine, elevated concentration of free fatty acids and defective insulin secretion influenced the appearance of impaired glucose tolerance in patients with hyperthyroidism. No relation was found, however, between the impaired glucose tolerance and the duration of hyperthyroidism or the age of patients.
对62例未经治疗的甲状腺功能亢进患者进行了研究，以探讨糖耐量受损的出现与甲状腺功能亢进持续时间、患者年龄、血清甲状腺素、三碘甲状腺原氨酸和游离脂肪酸浓度，以及基础胰岛素分泌和口服及静脉注射葡萄糖刺激后的胰岛素分泌等因素之间的关系。对照组由24名进行了口服和静脉葡萄糖耐量试验的健康受试者组成。在研究的因素中，血清甲状腺素和三碘甲状腺原氨酸浓度高、游离脂肪酸浓度升高以及胰岛素分泌缺陷影响了甲状腺功能亢进患者糖耐量受损的出现。然而，未发现糖耐量受损与甲状腺功能亢进持续时间或患者年龄之间存在关联。
