Covelli V, Massari F, D'Andrea L, Cervo M A, Buscaino G A, Jirillo E
Department of Neurology, 2nd Medical School, University Federico II, Naples, Italy.
Int J Neurosci. 1994 Mar;75(1-2):139-43. doi: 10.3109/00207459408986297.
Patients with migraine headaches show significantly lower prevalence of malignant neoplasms when compared with the general control group or the age-matched control group. Conversely, no significant difference concerning the family history for neoplasms has been found between the two groups. Nevertheless, headache and cancer in a family member in migraneous are not coexistent. Although more extensive, epidemiological studies are necessary to confirm our data, it is suggested that some particular biochemical or psychologic aspects involved in the pathogenesis of migraine might represent the presence of a protective factor against neoplasm development.
与普通对照组或年龄匹配的对照组相比，偏头痛患者的恶性肿瘤患病率显著更低。相反，两组之间在肿瘤家族史方面未发现显著差异。然而，偏头痛患者家族中的头痛与癌症并非并存。尽管需要更广泛的流行病学研究来证实我们的数据，但有迹象表明，偏头痛发病机制中涉及的某些特定生化或心理因素可能代表着一种针对肿瘤发生的保护因素。
