Gliantsev S P, Annaev A G, Savvina T V
Biull Eksp Biol Med. 1993 Jan;115(1):65-7.
Morphological evaluation of composition and structure of a biologically active compound (BAC) based on sodium alginate, comprising 1% sizomycin and 0.25% protease C, on wound healing in infected rats wounds was made in experiment. The results have clearly shown that for the infected wound treatment during the first period of wound healing BAC of polyfunctional action must be applied. Biologically active substances (sizomycin and protease C) promote removal of inflammatory etiopathogenic factors, i. e. necrotic tissues and microbic bodies, while polysaccharide basis of the composition promotes stimulation of reparative processes in the wounds. Powder with granules size 315 m including 24% potassium gluconate is believed most suitable BAC structure.
对一种基于海藻酸钠的生物活性化合物（BAC）进行了形态学评估，该化合物包含1%的西佐霉素和0.25%的蛋白酶C，用于实验性感染大鼠伤口的愈合。结果清楚地表明，在伤口愈合的第一阶段治疗感染伤口时，必须应用具有多功能作用的BAC。生物活性物质（西佐霉素和蛋白酶C）促进炎症致病因素的清除，即坏死组织和微生物体，而该组合物的多糖基础促进伤口修复过程的刺激。粒度为315微米且包含24%葡萄糖酸钾的粉末被认为是最合适的BAC结构。
