Shigenobu M, Teramoto S
Department of Cardiovascular Surgery, Okayama University Medical School, Japan.
Surg Today. 1994;24(1):1-5. doi: 10.1007/BF01676876.
We studied 100 patients who underwent an isolated aortic valve replacement (AVR) between 1974 and 1991. The patients were divided into the following two groups and compared: group A, which consisted of 40 patients operated on before 1978 who underwent continuous left coronary perfusion with blood; and group B, which consisted of 60 patients operated on after 1979 in whom St. Thomas solution was used in combination with topical cardiac cooling. Moreover, we divided the group B patients into two subgroups: group B1, who underwent AVR before 1986 during which we administered St. Thomas solution with ice slush every 30 min; and group B2, who had AVR after 1986 in which we used St. Thomas solution with a cold saline (4 degrees C) solution and treated with a small amount of slushed ice very 15 min. The incidence of supraventricular tachycardias was 15% in group A, 50% in group B1, and 15% in group B2. The severity of preoperative New York Heart Association (NYHA) functional class, the type of valve lesions, cardiothoracic ratio, left ventricular function, aortic clamp time, bypass time, and use of drugs did not correlate with the incidence of supraventricular tachycardias in either group A or B. In group B2 patients, we paid a lot of attention to cooling the right atrium as well as the left ventricle by immersing the whole heart using a 4 degrees C saline solution, which led to a remarkable reduction of the incidence of supraventricular tachycardia. This fact indicates that right atrial preservation is one of the most important factors for reducing the incidence of supraventricular tachycardia.
我们研究了1974年至1991年间接受单纯主动脉瓣置换术(AVR)的100例患者。将患者分为以下两组并进行比较:A组,由1978年前接受手术的40例患者组成,术中进行持续左冠状动脉血液灌注;B组,由1979年后接受手术的60例患者组成,术中使用圣托马斯液并联合局部心脏降温。此外,我们将B组患者分为两个亚组:B1组,1986年前接受AVR,术中每30分钟给予含碎冰的圣托马斯液;B2组,1986年后接受AVR,术中使用含冷盐水(4℃)的圣托马斯液并每15分钟用少量碎冰处理。A组室上性心动过速的发生率为15%,B1组为50%,B2组为15%。A组和B组术前纽约心脏协会(NYHA)功能分级的严重程度、瓣膜病变类型、心胸比率、左心室功能、主动脉阻断时间、体外循环时间和药物使用情况均与室上性心动过速的发生率无关。在B2组患者中,我们通过使用4℃盐水溶液浸泡整个心脏,非常重视右心房和左心室的降温,这导致室上性心动过速的发生率显著降低。这一事实表明,保留右心房是降低室上性心动过速发生率的最重要因素之一。