Antibodies to part of the Rho antigen complex occurring in two women with Rho variants.

Two women with Rho variants are reported. Both had received transfusions and had anti-Rh antibodies. One was found to have anti-Rh-ACD and anti-Jk-a and represents a phenotype not reported previously. The other was the mother of a child with a mild hemolytic disease caused by anti-Rh-CD. Family studies of both patients showed transmission of Rh-cd but not Rh-acd. Emphasis is placed on transfusing Rho negative blood to Rho variants lacking any or all of factors Rh-A, Rh-B, Rh-C and Rh-D.