Mayberry R M
Emory University School of Public Health, Division of Epidemiology, Atlanta, GA 30329.
Ann Epidemiol. 1994 May;4(3):205-13. doi: 10.1016/1047-2797(94)90098-1.
Data from the 1980 to 1982 population-based Cancer and Steroid Hormone case-control study of women 20 to 54 years old afforded the opportunity to investigate risk factors for breast cancer among black women younger than 40 years (177 patients and 137 control subjects) and to compare the results to black women 40 to 54 years old (313 patients and 348 control subjects). Information on exposure variables was obtained by in-person interviews. The logistic regression results indicated that the risk of breast cancer among black women younger than 40 years was nearly three times greater for those who used oral contraceptives for more than 10 years relative to never-users (odds ratio, 2.8; 95% confidence interval, 1.2 to 6.8) and more than four times greater for severely obese women (body mass index > or = 32.30 kg/m2) relative to women whose relative weights were less than 24.90 kg/m2. Patterns of association for the two age groups were similar for surgical menopausal, age at first full-term pregnancy, and multiple births, but differed for age at menarche.
1980年至1982年针对20至54岁女性开展的基于人群的癌症与类固醇激素病例对照研究数据，提供了调查40岁以下黑人女性乳腺癌风险因素（177例患者和137例对照对象）并将结果与40至54岁黑人女性（313例患者和348例对照对象）进行比较的机会。通过面对面访谈获取暴露变量信息。逻辑回归结果表明，40岁以下使用口服避孕药超过10年的黑人女性患乳腺癌的风险相对于从未使用者而言几乎高出三倍（比值比为2.8；95%置信区间为1.2至6.8），而重度肥胖女性（体重指数≥32.30kg/m²）相对于相对体重低于24.90kg/m²的女性，患乳腺癌的风险高出四倍多。两个年龄组在手术绝经、首次足月妊娠年龄和多胎生育方面的关联模式相似，但初潮年龄方面有所不同。
