Rosen G, Holmes E C, Forscher C A, Lowenbraun S, Eckardt J J, Eilber F R
Cedars-Sinai Comprehensive Cancer Center, Los Angeles, California.
Chest Surg Clin N Am. 1994 Feb;4(1):75-83.
Fifty percent of patients with osteogenic sarcoma who develop pulmonary metastases are salvageable with continued effective chemotherapy and thoracotomies, as long as good local control is achieved in the primary tumor. In patients presenting with simultaneous primary tumor and pulmonary metastatic disease, the cure rate is potentially as high as it is in those patients who present with primary tumor alone. However, in the latter patients, curative surgery must be done to obtain permanent local control for the primary tumor, and thoracotomy must be performed to remove residual disease to ensure against recurrent disease.
只要原发肿瘤实现良好的局部控制，50%发生肺转移的骨肉瘤患者可通过持续有效的化疗和开胸手术进行挽救性治疗。对于同时出现原发肿瘤和肺转移疾病的患者，治愈率可能与仅出现原发肿瘤的患者一样高。然而，对于后一组患者，必须进行根治性手术以实现原发肿瘤的永久局部控制，并且必须进行开胸手术以切除残留病灶，确保防止疾病复发。
