Yamabe T, Nagata S, Ishikura F, Kimura K, Miyatake K
Department of Medicine, Hiroshima University School of Medicine, Japan.
Cathet Cardiovasc Diagn. 1994 Apr;31(4):270-6. doi: 10.1002/ccd.1810310405.
To evaluate the influence of intra-balloon pressure on the development of severe mitral regurgitation (> or = grade 3+), we measured intraballoon pressure during percutaneous transvenous mitral commissurotomy (PTMC) in 62 patients using the Inoue balloon catheter. The peak intraballoon pressure was 2.29 +/- 0.55 kg/cm2. Severe mitral regurgitation as a result of leaflet tear occurred in 7 patients (11%). Patients were divided into two groups those with (n = 7) and those without (n = 55) severe mitral regurgitation. Intraballoon pressure had been significantly higher in those with vs. those without severe mitral regurgitation (2.76 +/- 0.31 kg/cm2 vs. 2.23 +/- 0.55 kg/cm2, P < 0.01). Multiple logistic regression analysis revealed that the occurrence of severe mitral regurgitation was related to only the peak intraballoon pressure. These data suggest that a high intraballoon pressure is a risk factor for severe mitral regurgitation as a result of leaflet tear.
为评估球囊内压力对严重二尖瓣反流（≥3+级）发展的影响，我们使用Inoue球囊导管对62例患者在经皮经静脉二尖瓣交界切开术（PTMC）期间测量了球囊内压力。球囊内峰值压力为2.29±0.55kg/cm²。7例患者（11%）因瓣叶撕裂出现严重二尖瓣反流。患者被分为两组，有严重二尖瓣反流的患者（n = 7）和无严重二尖瓣反流的患者（n = 55）。有严重二尖瓣反流的患者的球囊内压力显著高于无严重二尖瓣反流的患者（2.76±0.31kg/cm²对2.23±0.55kg/cm²，P < 0.01）。多因素逻辑回归分析显示，严重二尖瓣反流的发生仅与球囊内峰值压力有关。这些数据表明，高球囊内压力是因瓣叶撕裂导致严重二尖瓣反流的一个危险因素。
