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心脏手术期间温心内灌注的血流动力学后果

Haemodynamic consequences of warm cardiac irrigation during cardiac surgery.

作者信息

Lingaraju N, Horrow J C, Colonna-Romano P, Strong M D

机构信息

Department of Anesthesiology, Hahnemann University, Philadelphia, PA 19102-1192.

出版信息

Can J Anaesth. 1994 May;41(5 Pt 1):384-6. doi: 10.1007/BF03009859.

Abstract

Following cardiopulmonary bypass (CPB) and prior to closing the chest, some surgeons irrigate the heart and pericardium with warm saline. This prospective study, using each patient as his own control, evaluated the haemodynamic effects of warm (44 +/- 5 degrees C) irrigation on the heart and pericardium following CPB. Following discontinuation of CPB, a Mon-a-therm model 6500 thermocouple monitor measured the myocardial septum and the irrigating fluid temperatures. Immediately before, during and two minutes after irrigation of the heart and pericardium, we measured heart rate (HR), systemic blood pressure (BP), pulmonary artery pressure (PAP), central venous pressure (CVP), thermodilution cardiac output, and calculated systemic vascular resistance (SVR). During warm irrigation, HR increased from 93 +/- 15 to 101 +/- 13 min-1 and systolic BP increased from 111 +/- 17 to 131 +/- 27 mmHg. After irrigation, HR decreased to 96 +/- 12 min-1 with no change in systolic BP. The calculated SVR after irrigation increased to 1117 +/- 413 dynes.sec.cm-5 from the pre-irrigation value of 821 +/- 243 dynes.sec.cm-5, while cardiac index decreased to 2.4 L.min-1.m-2 from its pre-irrigation value of 2.99 L.min-1.m-2. Warm irrigation of the pericardial pouch causes tachycardic and hypertensive responses in patients undergoing cardiac surgery.

摘要

在体外循环(CPB)后且在关闭胸腔之前,一些外科医生用温盐水冲洗心脏和心包。这项前瞻性研究以每位患者自身作为对照,评估了CPB后温(44±5℃)冲洗对心脏和心包的血流动力学影响。在CPB停止后,使用Mon-a-therm 6500型热电偶监测仪测量心肌间隔和冲洗液温度。在冲洗心脏和心包之前、期间以及冲洗后两分钟,我们测量了心率(HR)、体循环血压(BP)、肺动脉压(PAP)、中心静脉压(CVP)、热稀释心输出量,并计算了体循环血管阻力(SVR)。在温冲洗期间,HR从93±15次/分钟增加到101±13次/分钟,收缩压从111±17 mmHg增加到131±27 mmHg。冲洗后,HR降至96±12次/分钟,收缩压无变化。冲洗后计算出的SVR从冲洗前的821±243达因·秒·厘米⁻⁵增加到1117±413达因·秒·厘米⁻⁵,而心脏指数从冲洗前的2.99升·分钟⁻¹·米⁻²降至2.4升·分钟⁻¹·米⁻²。对心包腔进行温冲洗会使心脏手术患者出现心动过速和高血压反应。

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