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[盆腔脏器清除术、发病率及生存率]

[Pelvic exenteration, morbidity and survival].

作者信息

Méndez L, Bernal A, Escudero P, González G, Fajardo A

机构信息

Servicio de Ginecología Oncológica, Hospital Luis Castelazo Ayala, México, D.F.

出版信息

Ginecol Obstet Mex. 1994 Jun;62:161-5.

PMID:8056362
Abstract

Between 1985 and 1990, 17 patients have undergone pelvic exenteration at the Obstetric and Gynecology Hospital 4, Mexican Social Security Institute, Mexico City. Sixteen patients had undergone radiation therapy previously. Most operative procedures were performed for cancer of the cervix, recurrent or persistent. The major type of pelvic neoplasm was epidermoid carcinoma, occurring in 15 patients. No exenterations were performed in presence of pelvic lymph nodes. Operative mortality was 5.8%. One or more major surgical complications occurred in nine patients, three patients required one or more surgical procedures to correct these complications. There was no mortality in patients undergoing reoperation. Nonsurgical complications were encountered in five patients. All patients were followed for at least 2 years or until time of death. The cumulative 5-year survival was significantly related to type of tumor. All patients with recurrent tumor were alive and disease free in the last follow-up compared to only 33% of patients with persistent tumor. Four patients underwent anterior surgical procedure, all with persistent tumour. Three had documented recurrence and none survived beyond 14 months.

摘要

1985年至1990年间,墨西哥社会保障局墨西哥城第四妇产科医院有17例患者接受了盆腔脏器清除术。16例患者此前接受过放射治疗。大多数手术是针对复发性或持续性宫颈癌进行的。盆腔肿瘤的主要类型是表皮样癌,有15例患者。存在盆腔淋巴结时不进行脏器清除术。手术死亡率为5.8%。9例患者发生了一种或多种严重手术并发症,3例患者需要进行一次或多次手术来纠正这些并发症。再次手术的患者无死亡病例。5例患者出现非手术并发症。所有患者均随访至少2年或直至死亡。累积5年生存率与肿瘤类型显著相关。与仅有33%的持续性肿瘤患者相比,所有复发性肿瘤患者在最后一次随访时均存活且无疾病。4例患者接受了前路手术,均为持续性肿瘤。3例有复发记录,无一例存活超过14个月。

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