Kagawa K, Arakawa M, Miwa H, Noda T, Nishigaki K, Ito Y, Hirakawa S
Second Department of Internal Medicine, Gifu University School of Medicine.
J Cardiol. 1994 Jul-Aug;24(4):317-25.
The left atrium (LA) stores part of the right ventricular stroke volume during ventricular systole for passive release into the left ventricle (LV) during ventricular early diastole and active release during ventricular late diastole (passive and active contraction). The rest of the right ventricular stroke volume flows through the LA from the pulmonary vascular bed to the LV (LA conduit function). The factors affecting these LA functions were evaluated during ventricular diastole by left atrial angiography and left ventriculography in 21 patients with normal LV ejection fraction (0.53-0.76), but without coronary artery disease and valvular heart disease, aged 40-70 years. LV stroke volume was calculated from left ventriculograms. The maximal LA volume, minimal LA volume, and LA volume at the beginning of the left atrial active contraction were calculated from the left atrial angiograms, and further corrected by a regression equation (true volume = 0.91 x calculated volume -1.1). The LA reservoir volume, LA passive contraction volume, LA active contraction volume, and LA conduit volume were obtained. LA conduit volume correlated significantly with LV stroke volume (r = 0.97), but not with maximal LA volume and LA reservoir volume. LA active contraction volume correlated significantly with LA reservoir volume, LA volume at the beginning of LA active contraction, and maximal LA volume (r = 0.85, 0.60, 0.54, respectively). LA passive contraction volume did not correlate with any factor, and was grossly independent of LV stroke volume. LA conduit volume may be associated with LV diastolic function, and LA active contraction volume appears to increase with increased LA volume.
左心房(LA)在心室收缩期储存部分右心室搏出量,以便在心室舒张早期被动释放至左心室(LV),并在心室舒张晚期主动释放(被动和主动收缩)。右心室搏出量的其余部分从肺血管床经左心房流入左心室(左心房管道功能)。在心室舒张期,通过左心房造影和左心室造影对21例左心室射血分数正常(0.53 - 0.76)、无冠状动脉疾病和瓣膜性心脏病、年龄在40 - 70岁的患者的这些左心房功能影响因素进行了评估。左心室搏出量根据左心室造影计算得出。左心房最大容积、最小容积以及左心房主动收缩开始时的容积根据左心房造影计算得出,并通过回归方程进一步校正(实际容积 = 0.91×计算容积 - 1.1)。得出左心房储备容积、左心房被动收缩容积、左心房主动收缩容积和左心房管道容积。左心房管道容积与左心室搏出量显著相关(r = 0.97),但与左心房最大容积和左心房储备容积无关。左心房主动收缩容积与左心房储备容积、左心房主动收缩开始时的容积以及左心房最大容积显著相关(分别为r = 0.85、0.60、0.54)。左心房被动收缩容积与任何因素均无相关性,且与左心室搏出量基本无关。左心房管道容积可能与左心室舒张功能有关,且左心房主动收缩容积似乎随左心房容积增加而增加。