Dadavani S A, Uspenskiĭ L V, Lapchinskiĭ V A, Ulíanov D A, Artiukhina E G
Khirurgiia (Mosk). 1994 May(5):36-8.
Experience in the treatment of 77 patients with diabetic angiopathy of the lower limbs is discussed. Various pyonecrotic complications developed in 44% of cases. Laboratory and instrumental diagnostic methods included general clinical, biochemical, and coagulation tests, angiography, dopplerography, and rheovasography. Rheovasography was elaborated in 1952 at the Facultative Surgical Clinic head by N. Elansky and is still an informative method. The management of patients with diabetic angiopathy included correction of carbohydrate metabolism, angioprotectors, anticoagulants, and anti-aggregation agents. In patients with pyonecrotic complications intraarterial infusion of the medicinal agents is preferred, the method is used in the clinic since 1951. Operations were performed on 74% of patients, the character of the intervention was determined by the affection of the vascular bed. Reconstructive operations were conducted on 16% of patients. In the absence of conditions for reconstruction lumbar sympathectomy was undertaken. According to indications, the operation was combined with necrotomy or "minor" amputations. Adequate non-operative therapy, improvement of circulation in the limb by reconstructive operations of sympathectomy save the limb or limit the volume of the amputation. Amputation through the middle third of the leg was performed in 7, exarticulation at Chopart's joint in 2 and at Lisfranc's joint in one, and exarticulation of the toes in 10 patients. No fatal outcomes occurred. The thigh was amputated in 13 patients with moist gangrene for vital indications, mortality was 45%. Timely recognition of affection of the arteries in diabetes mellitus is recommended for determining the indications for operative interventions aimed at preventing pyonecrotic complications.
讨论了77例糖尿病下肢血管病变患者的治疗经验。44%的病例出现了各种脓性坏死并发症。实验室和仪器诊断方法包括一般临床、生化和凝血检查、血管造影、多普勒超声检查和血流容积描记法。血流容积描记法于1952年由N. 埃兰斯基在兼治外科诊所首创,至今仍是一种有价值的方法。糖尿病血管病变患者的治疗包括纠正碳水化合物代谢、使用血管保护剂、抗凝剂和抗聚集剂。对于有脓性坏死并发症的患者,首选动脉内输注药物,该方法自1951年起在诊所使用。74%的患者接受了手术,干预的性质取决于血管床的病变情况。16%的患者进行了重建手术。在无法进行重建手术的情况下,进行了腰交感神经切除术。根据适应证,该手术与坏死组织切除术或“小”截肢术联合进行。充分的非手术治疗、通过重建手术或交感神经切除术改善肢体循环,可保住肢体或限制截肢范围。7例患者在小腿中部三分之一处进行了截肢,2例在Chopart关节离断,1例在Lisfranc关节离断,10例患者进行了趾离断。无死亡病例。13例湿性坏疽患者因生命指征进行了大腿截肢,死亡率为45%。建议及时识别糖尿病患者的动脉病变,以确定旨在预防脓性坏死并发症的手术干预适应证。