Hernádi L, Töröcsik M, Pláyerné Dorkó A
Heves Megyei Onkormányzat Markhot Ferenc Kórház-Rendelöintézet, Szülészeti és Nögyógyászati Osztály, Eger.
Orv Hetil. 1994 Jul 10;135(28):1521-6.
The increased resolution of transvaginal sonography allows a detailed evaluation of fetal anatomy in the first trimester of pregnancy. According to the authors experiences screening for fetal anomalies is a real possibility when the fetus is bigger than 50 mms in size (crownrump-length). A prospective study was started in February 1992. Since that time transvaginal sonography has been offered to every woman in the 12th week of their pregnancies. Twenty structural anomalies have been diagnosed in 18 fetuses during a 17-month period. Besides of detecting "classical" congenital anomalies, nuchal oedema is considered to be a promising sign for screening chromosomal abnormalities especially Down syndrome. In this series 4 cases of trisomy 21 has been diagnosed by karyotyping in the presence of nuchal oedema. The results of their study suggest, that more and more fetal anomalies can be detected in the first trimester of pregnancy, therefore transvaginal sonography is offered to use as a screening method, being a powerful diagnostic tool for early diagnosis.
经阴道超声分辨率的提高使得在妊娠早期能够对胎儿解剖结构进行详细评估。根据作者的经验，当胎儿大小超过50毫米（头臀长）时，对胎儿异常进行筛查是切实可行的。一项前瞻性研究于1992年2月启动。从那时起，在妊娠第12周时，每位孕妇都接受了经阴道超声检查。在17个月的时间里，在18例胎儿中诊断出20种结构异常。除了检测“经典”先天性异常外，颈部水肿被认为是筛查染色体异常尤其是唐氏综合征的一个有前景的指标。在这个系列中，有4例21三体综合征是在存在颈部水肿的情况下通过核型分析诊断出来的。他们的研究结果表明，在妊娠早期可以检测到越来越多的胎儿异常，因此经阴道超声作为一种筛查方法被提供使用，它是早期诊断的有力诊断工具。
