McCabe M S, Varricchio C G, Padberg R M
Community Oncology and Rehabilitation Branch, National Cancer Institute, Bethesda, MD 20892.
Semin Oncol Nurs. 1994 May;10(2):123-9. doi: 10.1016/s0749-2081(05)80066-x.
Clinical trials are vital for the development of state-of-the-art cancer prevention and treatment. A goal for trial recruitment should be to have a representative sample of the total population by gender, race, culture, ethnicity, and socioeconomic status as appropriate. Increased sensitivity to the unique barriers and access to care issues required to achieve a representative sample are necessary. Knowledge and understanding of recruitment problems and strategies to resolve them are developing; however, much more is needed before we can fully address and resolve all of the relevant issues. Nurses have a key role in identification, education, and recruitment of special populations including the SED to clinical trials.
临床试验对于先进癌症预防和治疗的发展至关重要。试验招募的一个目标应该是根据性别、种族、文化、族裔和社会经济地位,适当地获得全体人群的代表性样本。提高对获得代表性样本所需的独特障碍和医疗服务可及性问题的敏感度是必要的。对招募问题及其解决策略的认识和理解正在不断发展;然而,在我们能够充分解决所有相关问题之前,仍有许多工作要做。护士在识别、教育和招募包括社会经济弱势群体在内的特殊人群参与临床试验方面发挥着关键作用。