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[急性感染性肺破坏患者肺实质的解毒功能]

[The detoxifying function of the pulmonary parenchyma in patients with acute infectious lung destruction].

作者信息

Bel'skikh A N, Gurevich K Ia, Tulupov A N, Kostiuchenko A L, Lishenko V V

出版信息

Anesteziol Reanimatol. 1994 Mar-Apr(2):18-9.

PMID:8059987
Abstract

The study of arteriovenous ratio of medium-molecular oligopeptides level in 32 patients with acute infectious lung destructions has established an important detoxicating role of the lungs in endotoxemia syndrome during pulmonary-pleural suppurations. It has been found that, with the pronounced endotoxemia syndrome, during catabolic phase of the disease the lungs turn from toxin filter into their source. Detoxicating capacity of the lung parenchyma was shown to be more dependent on the severity of general metabolic disturbances than on the dissemination of suppurative lung destruction.

摘要

对32例急性感染性肺破坏患者中分子寡肽水平动静脉比的研究表明,在肺胸膜化脓期间,肺在内毒素血症综合征中具有重要的解毒作用。研究发现,在内毒素血症综合征明显时,在疾病的分解代谢阶段,肺从毒素过滤器转变为毒素来源。肺实质的解毒能力显示,其更多地取决于全身代谢紊乱的严重程度,而非化脓性肺破坏的扩散程度。

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