Bogoiavlenskiĭ I F, Zaks I O
Anesteziol Reanimatol. 1994 Mar-Apr(2):59-64.
The review of Russian and foreign literature published in 1939 to 1993 has demonstrated possible use of small doses of isotonic salt solution for prompt correction of hemodynamic parameters in severe traumas, massive blood loss, most severe stages of shock and critical conditions. The best effect can be achieved with the use of isotonic salt solutions in combination with hyperoncotic solutions (sodium chloride and low molecular weight dextran). The principal mechanism of action is attraction of the liquid from the interstitial spaces into the vascular bed, stimulation of vascular osmoreceptors and neurogenic reflex mechanisms. High efficacy, simplicity and acceptability of the technique make it possible to recommend it for the use at prehospital stage, immediately on the spot of the accident, during transportation and at hospital stage when there are numerous patients with severe traumas and shortage of infusion-transfusion media.
对1939年至1993年发表的俄罗斯和国外文献的综述表明，小剂量等渗盐溶液可用于在严重创伤、大量失血、休克最严重阶段和危急情况下迅速纠正血流动力学参数。将等渗盐溶液与高渗溶液（氯化钠和低分子右旋糖酐）联合使用可取得最佳效果。其主要作用机制是将组织间隙中的液体吸引到血管床，刺激血管渗透压感受器和神经反射机制。该技术具有高效、简便和可接受性，因此可以推荐在院前阶段、事故现场即刻、运输过程中以及医院阶段使用，此时有大量严重创伤患者且输液输血介质短缺。
