Kubo O, Takakura K
Dept. of Neurosurgery, Tokyo Women's Medical College.
Gan To Kagaku Ryoho. 1994 Aug;21(10):1583-92.
The pathophysiology and treatment of malignant brain tumors (malignant glioma, metastatic brain tumor and malignant lymphoma) were discussed. In order to improve the prognosis of malignant brain tumor patients, many clinical trials have been conducted. The most acceptable treatment for malignant glioma is surgical resection plus radiochemotherapy with ACNU. A multidisciplinary approach to treatment is important for control of metastatic brain tumors. Treatment of malignant lymphoma includes radiotherapy and chemotherapy in combination. Combination chemotherapy with CHOP is more effective for malignant lymphoma.
讨论了恶性脑肿瘤(恶性胶质瘤、脑转移瘤和恶性淋巴瘤)的病理生理学及治疗方法。为改善恶性脑肿瘤患者的预后,已开展了许多临床试验。恶性胶质瘤最可接受的治疗方法是手术切除加用阿糖胞苷进行放化疗。多学科治疗方法对控制脑转移瘤很重要。恶性淋巴瘤的治疗包括放疗和化疗联合应用。CHOP联合化疗对恶性淋巴瘤更有效。