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与肺炎球菌菌血症相关的严重自身免疫性溶血性贫血。

Severe autoimmune hemolytic anemia associated with pneumococcal bacteremia.

作者信息

Cáceres W

机构信息

Hematology Division, San Juan City Hospital, Puerto Rico.

出版信息

Bol Asoc Med P R. 1993 Jan-Mar;85(1-3):16-7.

PMID:8060437
Abstract

Acquired autoimmune hemolytic anemia frequently occurs in an individual with a deranged immune system. This impaired immune system can also predispose the patient to infections with a wide range of organisms. Also, it is known that certain infectious organisms can induce immune hemolytic anemia in normal hosts by diverse mechanisms. When autoimmune hemolytic anemia presents concomitantly with infection, it is extremely difficult to establish the etiology of the condition. We present a case of severe autoimmune hemolytic anemia of the warm antibody type associated with pneumococcal sepsis in which both the infectious process and the hemolysis are probably secondary to an altered immune system.

摘要

获得性自身免疫性溶血性贫血常发生于免疫系统紊乱的个体。这种受损的免疫系统也会使患者易感染多种病原体。此外,已知某些感染性病原体可通过多种机制在正常宿主中诱发免疫性溶血性贫血。当自身免疫性溶血性贫血与感染同时出现时,极难确定该病症的病因。我们报告一例与肺炎球菌败血症相关的严重温抗体型自身免疫性溶血性贫血病例,其中感染过程和溶血可能均继发于免疫系统改变。

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