Sjöberg B J, Ask P, Loyd D, Wranne B
Department of Clinical Physiology, Linköping University, Sweden.
J Am Soc Echocardiogr. 1994 May-Jun;7(3 Pt 1):276-85. doi: 10.1016/s0894-7317(14)80398-2.
With time-corrected color Doppler echocardiography, the aortic subvalvular spatial flow velocity profile was registered in two perpendicular planes in 10 patients with aortic valve disease and in 5 healthy control subjects. Patients with predominant aortic valve stenosis had a fairly flat profile, and the subvalvular diameter, obtained from left parasternal two-dimensional tissue imaging, provided a good estimate of the mean of the two transverse flow axes. This explains the accuracy in determination of stroke volume and aortic valve area that is reported in studies on patients with aortic valve stenosis when the continuity equation is used. However, the use of apical pulsed Doppler ultrasound registrations from the left ventricular outflow tract and parasternal two-dimensional echocardiography for flow area calculation may introduce large errors in calculated stroke volume in certain patients with aortic regurgitation and in normal subjects, because of a non-flat spatial velocity profile or an inaccurate estimate of flow area.
采用时间校正彩色多普勒超声心动图，在10例主动脉瓣疾病患者和5例健康对照者的两个相互垂直平面上记录主动脉瓣下空间流速剖面。以主动脉瓣狭窄为主的患者流速剖面相当平坦，从胸骨旁二维组织成像获得的瓣下直径能很好地估计两个横向流轴的平均值。这就解释了在使用连续性方程研究主动脉瓣狭窄患者时，报告的每搏量和主动脉瓣面积测定的准确性。然而，对于某些主动脉瓣反流患者和正常受试者，由于空间速度剖面不平坦或流面积估计不准确，使用经心尖脉冲多普勒超声从左心室流出道进行记录以及胸骨旁二维超声心动图来计算流面积，可能会在计算每搏量时引入较大误差。
