Donabedian H, O'Donnell E, Olszewski C, MacArthur R D, Budd N
Department of Medicine, Medical College of Ohio, Toledo 43699.
Diagn Microbiol Infect Dis. 1994 Feb;18(2):111-5. doi: 10.1016/0732-8893(94)90075-2.
We report the first proven case of Sporothrix meningoencephalitis in an AIDS patient. The patient had dramatic, wide-spread ulcerative and infiltrative disease with progressive meningoencephalitis in spite of amphotericin and itraconazole therapy. Sporothrix was cultured from premortem cerebrospinal fluid and seen in the meninges and in brain vessels at autopsy.