Bonnin F, Buvat I, Benali H, Di Paola R
INSERM U66, Institut Gustave-Roussy, Villejuif, France.
Eur J Nucl Med. 1994 May;21(5):388-93. doi: 10.1007/BF00171412.
Phantom studies have demonstrated that factor analysis of medical image sequences using target apex-seeking (FAMIS-TAS) applied to spectral scintigraphic image sequences is an efficient adaptive scatter correction method. We assessed the improvement in quality of clinical images using FAMIS-TAS as compared with two other scatter correction techniques: conventional 20% photopeak window (PW) and scatter window subtraction (SWS). Thirty normal technetium-99m hydroxymethylene diphosphonate bone scans were processed. Bone to soft tissue contrasts and signal-to-noise and contrast-to-noise ratios were measured. The overall image quality was evaluated using an observer testing questionnaire submitted to four physicians. Quantitative parameters showed that FAMIS-TAS images displayed the best bone to soft tissue contrasts and contrast-to-noise ratios, but the lowest signal-to-noise ratios. PW images presented the lowest contrasts and contrast-to-noise ratios, and the highest signal-to-noise ratios. SWS gave intermediate results. According to the observer testing results, PW images showed the lowest bone to soft tissue contrasts and the highest signal-to-noise ratios. FAMIS-TAS images showed the lowest signal-to-noise ratios. The images processed by the three methods displayed the same anatomical information.
模拟研究表明，将应用于频谱闪烁图像序列的目标顶点搜索医学图像序列因子分析（FAMIS-TAS）作为一种有效的自适应散射校正方法。我们评估了与其他两种散射校正技术相比，使用FAMIS-TAS对临床图像质量的改善：传统的20%光电峰窗（PW）和散射窗减法（SWS）。对30例正常的99m锝亚甲基二膦酸盐骨扫描进行了处理。测量了骨与软组织对比度、信噪比和对比噪声比。使用提交给四位医生的观察者测试问卷对整体图像质量进行评估。定量参数显示，FAMIS-TAS图像显示出最佳的骨与软组织对比度和对比噪声比，但信噪比最低。PW图像的对比度和对比噪声比最低，信噪比最高。SWS给出了中间结果。根据观察者测试结果，PW图像显示出最低的骨与软组织对比度和最高的信噪比。FAMIS-TAS图像的信噪比最低。三种方法处理的图像显示相同的解剖信息。
