聚乙二醇增强人血影蛋白的自我缔合
Enhancement of self-association of human spectrin by polyethylene glycol.
作者信息
Cole N, Ralston G B
机构信息
Department of Biochemistry, University of Sydney, Australia.
出版信息
Int J Biochem. 1994 Jun;26(6):799-804. doi: 10.1016/0020-711x(94)90109-0.
PMID:8063007
Abstract
- In the presence of polyethylene glycol, the self-association of human spectrin is enhanced in a manner that depends approx. exponentially on the mass concentration of polyethylene glycol. 2. For a given mass concentration, the enhancement is independent of the molecular weight of the polyethylene glycol. 3. These data are consistent with the operation of excluded volume effects, and support the contention that the association of spectrin is likely to be increased in the presence of the high concentration of hemoglobin within the erythrocyte in vivo.
摘要
- 在聚乙二醇存在的情况下，人血影蛋白的自缔合作用以一种大致呈指数方式依赖于聚乙二醇质量浓度的方式增强。2. 对于给定的质量浓度，这种增强作用与聚乙二醇的分子量无关。3. 这些数据与排除体积效应的作用相符，并支持这样的观点，即在体内红细胞内高浓度血红蛋白存在的情况下，血影蛋白的缔合作用可能会增强。
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