Oriol A, Ribera J M, Hernández A, Soriano V, Millá F, Feliu E
Service of Hematology, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain.
Haematologica. 1994 Mar-Apr;79(2):168-9.
Recent reports suggest that non-A, non-B, non-C viruses might not be uncommon etiologic agents of hepatitis-associated aplastic anemia. A 52-year-old woman without previous contact with toxic substances or drugs developed severe aplastic anemia sixteen days after the onset of acute hepatitis. Even after exhaustive serologic testing for hepatotropic viruses and PCR study for hepatitis C virus the etiologic agent could not be demonstrated. Evolution was fatal despite treatment. In this case the time lapse between the onset of hepatitis and the development of aplasia was shorter than in previously referred incidents. This fact supports the hypothesis that different non-A, non-B, non-C agents might be implicated in hepatitis-associated aplasia.
最近的报告表明，非甲、非乙、非丙型病毒可能是与肝炎相关的再生障碍性贫血的常见病原体。一名52岁女性，既往无接触有毒物质或药物史，在急性肝炎发病16天后出现严重再生障碍性贫血。即使对嗜肝病毒进行了详尽的血清学检测，并对丙型肝炎病毒进行了PCR研究，仍未能证实病原体。尽管进行了治疗，但病情仍发展至死亡。在该病例中，肝炎发作至再生障碍出现的时间间隔比之前报告的病例更短。这一事实支持了不同的非甲、非乙、非丙型病原体可能与肝炎相关再生障碍有关的假说。
