Morita K, Kudo H, Fujii K, Okamoto H, Matsubara K, Kanauchi H, Imamura S
Department of Dermatology, Faculty of Medicine, Kyoto University, Japan.
J Dermatol. 1994 Jun;21(6):442-6. doi: 10.1111/j.1346-8138.1994.tb01771.x.
We report a case of malignant melanoma of unknown primary origin which presented with a giant metastatic tumor in his right inguinal region. A 94-year-old man noticed a small subcutaneous tumor in the right inguinal region 3 years earlier, which eventually became as larger as 9 cm in diameter without treatment. Although a histological examination of the lesion showed malignant melanoma, extensive examination did not reveal its primary lesion or any metastasis other than that to the right inguinal area. Our case took an interesting course in that this well-growing metastatic tumor was localized in only one region and supported a previous report indicating that malignant melanoma with unknown primary origin has a low tendency to metastasize and a relatively good prognosis.
我们报告一例原发灶不明的恶性黑色素瘤病例,该病例表现为右侧腹股沟区巨大转移瘤。一名94岁男性3年前注意到右侧腹股沟区有一个小的皮下肿物,未经治疗最终直径增大至9厘米。尽管对该病变的组织学检查显示为恶性黑色素瘤,但全面检查未发现其原发灶或除右侧腹股沟区以外的任何转移灶。我们的病例病程有趣,在于这个生长良好的转移瘤仅局限于一个区域,这支持了之前的一份报告,该报告指出原发灶不明的恶性黑色素瘤转移倾向低且预后相对较好。