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职业性噪声暴露与血压

Occupational noise exposure and blood pressure.

作者信息

Fogari R, Zoppi A, Vanasia A, Marasi G, Villa G

机构信息

Department of Internal Medicine and Therapeutics, University of Pavia, Italy.

出版信息

J Hypertens. 1994 Apr;12(4):475-9.

PMID:8064173
Abstract

OBJECTIVE

To investigate the relationship between occupational noise exposure and blood pressure.

METHODS

We studied 8811 workers at a metallurgical factory, who were exposed to different levels of noise at the worksite: < or = 80 dB for 8078 workers and > 80 dB for 733 workers. A clinical examination, including measurements of blood pressure (by mercury sphygmomanometer, Korotkoff phases I and V), heart rate (by pulse palpation), body weight and height, was performed. The subjects were stratified into four age groups (18-30, 31-40, 41-50 and > 50 years) and into two body mass index groups: normal weight (< or = 25 kg/m2) and overweight (> 25 kg/m2). In order to eliminate possible confounding factors and statistical bias, a retrospective case versus control analysis was also carried out.

RESULTS

The epidemiologic approach showed that the systolic blood pressure (SBP) but neither the diastolic blood pressure (DBP) nor the heart rate values were statistically higher in the group who were exposed to noise levels of > 80 dB, although the difference could be considered clinically relevant only in the older age group. The prevalence of hypertension (according to World Health Organization criteria) was higher among the workers who were exposed to the higher levels of noise. Stratification for body mass index confirmed the existence of a higher prevalence of hypertension in the exposed group. The results from the case versus control analysis indicated that both the SBP and the DBP levels in the exposed group were significantly higher than those in the reference group, and confirmed the existence of a higher prevalence of hypertension in the exposed group.

CONCLUSIONS

The present data suggest that occupational exposure to noise levels exceeding 80 dB may lead to a higher prevalence of hypertension and to increased blood pressure values, although the results appear quantitatively different according to the approach that is taken to the problem (i.e. the epidemiologic or the case versus control approach).

摘要

目的

探讨职业性噪声暴露与血压之间的关系。

方法

我们研究了一家冶金厂的8811名工人,他们在工作场所接触不同水平的噪声:8078名工人接触噪声水平≤80分贝,733名工人接触噪声水平>80分贝。进行了临床检查,包括测量血压(使用汞柱式血压计,柯氏音第一相和第五相)、心率(通过脉搏触诊)、体重和身高。受试者被分为四个年龄组(18 - 30岁、31 - 40岁、41 - 50岁和>50岁)以及两个体重指数组:正常体重(≤25 kg/m²)和超重(>25 kg/m²)。为了消除可能的混杂因素和统计偏差,还进行了回顾性病例对照分析。

结果

流行病学方法显示,接触噪声水平>80分贝的组中,收缩压(SBP)在统计学上较高,但舒张压(DBP)和心率值在统计学上并未升高,不过这种差异仅在老年组中可被认为具有临床相关性。根据世界卫生组织标准,高血压患病率在接触较高水平噪声的工人中更高。按体重指数分层证实了暴露组中高血压患病率较高。病例对照分析结果表明,暴露组的SBP和DBP水平均显著高于参照组,并证实了暴露组中高血压患病率较高。

结论

目前的数据表明,职业性接触超过80分贝的噪声水平可能导致高血压患病率升高和血压值升高,尽管根据处理该问题的方法(即流行病学方法或病例对照方法),结果在数量上似乎有所不同。

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