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苹果酸柠檬酸钙补充试验:支持在儿童和青少年时期提高钙推荐膳食摄入量的证据。

Supplementation trials with calcium citrate malate: evidence in favor of increasing the calcium RDA during childhood and adolescence.

作者信息

Andon M B, Lloyd T, Matkovic V

机构信息

Procter & Gamble Company, Sharon Woods Technical Center, Cincinnati, OH 45242.

出版信息

J Nutr. 1994 Aug;124(8 Suppl):1412S-1417S. doi: 10.1093/jn/124.suppl_8.1412S.

DOI:10.1093/jn/124.suppl_8.1412S
PMID:8064394
Abstract

The vast majority of peak adult bone mass is accumulated by the time longitudinal growth is complete. As peak bone mass is an important determinant of future fracture risk, the goal of the current calcium recommended dietary allowance during youth is to provide a calcium intake that allows individuals to reach their full genetic potential for acquiring skeletal mass. The advent of controlled trials of calcium supplementation and total body bone mass measurements in children and adolescents provide the first direct way of determining the amount of calcium necessary to achieve optimal skeletal accretion. These studies indicate that the current RDAs are insufficient to support optimal bone mass gain during growth and development. Based on the recent intervention trials, recommendations are made for an RDA of 1250 mg during childhood and 1450 mg during adolescence. These values are consistent with established calcium balance intake thresholds for growth during pre-adolescence and adolescence.

摘要

绝大多数成年人的骨峰值是在纵向生长完成时积累的。由于骨峰值是未来骨折风险的重要决定因素,因此目前青少年钙的推荐膳食摄入量目标是提供一种钙摄入量,使个体能够充分发挥其获取骨骼质量的遗传潜力。针对儿童和青少年进行的钙补充剂对照试验以及全身骨量测量的出现,提供了确定实现最佳骨骼生长所需钙量的第一种直接方法。这些研究表明,目前的膳食推荐摄入量不足以支持生长发育期间的最佳骨量增加。基于最近的干预试验,建议儿童期的膳食推荐摄入量为1250毫克,青春期为1450毫克。这些数值与青春期前和青春期生长期间既定的钙平衡摄入阈值一致。

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