Rau W, Müller H E
Experientia. 1975 May 15;31(5):515-6. doi: 10.1007/BF01932430.
It was shown that neuraminidase of Vibrio comma is inactivated by Ca..-binding anions like citrate, EDTA, oxalate, phosphate or tartrate. There is, however, no inhibition of the newly described enzymes of Erysipelothrix insidiosa and Streptococcus viridans. Pyruvate and, to a lesser extent, also citrate inactivate all the neuraminidases investigated independently of their activation by Ca..ions.
已表明,霍乱弧菌的神经氨酸酶可被柠檬酸、乙二胺四乙酸、草酸盐、磷酸盐或酒石酸盐等与钙结合的阴离子灭活。然而,新近描述的豕丹毒杆菌和绿色链球菌的酶却不受抑制。丙酮酸以及程度稍轻的柠檬酸,可使所有被研究的神经氨酸酶失活,且与钙离子对它们的激活作用无关。