Anderson C J, Sturm R J, Shapiro M B, Ballew C
Department of Ophthalmology, University of Wisconsin, Madison.
J Cataract Refract Surg. 1994 May;20(3):295-8. doi: 10.1016/s0886-3350(13)80581-0.
A prospective, randomized, double-masked clinical trial of 182 patients compared the frequency of visual disturbances associated with two small incision intraocular lenses (IOLs): the Alcon MZ20BD 5 mm x 6 mm oval-optic poly(methyl methacrylate) (PMMA) IOL and the STAAR AQ1016 round-optic silicone IOL. The samples were similar at baseline. There were no significant differences in visual acuity, mean keratometric cylinder, or surgically induced cylinder between the two groups postoperatively. Patients completed a satisfaction questionnaire and visual symptom inventory of ten items three months postoperatively. Those with the oval-optic PMMA IOL reported significantly more visual symptoms than those with the round-optic silicone IOL (P = .03). The oval-optic group reported three symptoms more frequently: reflections, halos or rings around lights, and objects at arm's length appearing blurry (P < or = .010). The status of the fellow eye (cataract or pseudophakic) did not differ by randomization group, and the distribution of visual symptoms did not differ by status of the fellow eye. Frequency and severity of visual complaints were modest overall; only 1% in each group was unsatisfied with the visual results.
一项针对182例患者的前瞻性、随机、双盲临床试验，比较了两种小切口人工晶状体（IOL）相关视觉障碍的发生频率：爱尔康MZ20BD 5毫米×6毫米椭圆形光学聚甲基丙烯酸甲酯（PMMA）人工晶状体和STAAR AQ1016圆形光学硅胶人工晶状体。样本在基线时相似。两组术后视力、平均角膜散光或手术诱导散光均无显著差异。患者在术后三个月完成了一份满意度问卷和一份包含十个项目的视觉症状清单。椭圆形光学PMMA人工晶状体组报告的视觉症状明显多于圆形光学硅胶人工晶状体组（P = 0.03）。椭圆形光学组更频繁报告三种症状：反光、灯光周围的光晕或光环以及一臂距离处的物体出现模糊（P≤0.010）。随机分组后，对侧眼状态（白内障或人工晶状体眼）在各随机分组间无差异，视觉症状分布也不因对侧眼状态而不同。总体而言，视觉投诉的频率和严重程度适中；每组中只有1%的患者对视觉结果不满意。
