McLucas B, McGill J
Department of Obstetrics and Gynecology, University of California at Los Angeles 90024.
J Reprod Med. 1994 May;39(5):373-6.
Clear margins are critical to the identification of complete excision of premalignant lesions on the cervix. Large loop excision of the transformation zone aids the pathologic evaluation of the excised specimen while it causes minimal thermal damage. Prior studies of loop excision were performed with a cutting current blended with a coagulating waveform to aid hemostasis. Blended current has higher voltage, which may cause tissue to stick to the electrode and produce thermal damage to the cervix. In this series, pure cutting current was used to excise the cervical transformation zone in 20 patients. The depth of thermal damage was studied in 6 patients; the average endocervical zone of damage was 0.47 mm and that of the exocervical zone, 0.43 mm. The base of the cervix could be examined with the colposcope for the presence of glands. None of our procedures was complicated by intraoperative or delayed bleeding. The preoperative injection of a vasoconstrictor into the cervical stroma is thought to aid the surgery by its hemostatic properties.
切缘清晰对于确定宫颈癌前病变是否完全切除至关重要。转化区大环形切除术有助于对切除标本进行病理评估,同时造成的热损伤最小。先前关于环形切除术的研究是使用混合了凝血波形的切割电流来辅助止血。混合电流具有更高的电压,这可能导致组织粘附在电极上并对宫颈造成热损伤。在本系列研究中,对20例患者使用纯切割电流切除宫颈转化区。对6例患者的热损伤深度进行了研究;宫颈管内平均损伤深度为0.47毫米,宫颈外平均损伤深度为0.43毫米。可以用阴道镜检查宫颈底部是否存在腺体。我们的手术均未出现术中或延迟出血并发症。术前向宫颈基质注射血管收缩剂被认为因其止血特性有助于手术。