Passaro M E, Steiger E, Curtas S, Seidner D L
Department of General Surgery, Cleveland Clinic Foundation, OH 44195.
JPEN J Parenter Enteral Nutr. 1994 May-Jun;18(3):240-2. doi: 10.1177/0148607194018003240.
There are multiple reports in the literature of vascular erosion in the innominate vein or superior vena cava from the use of temporary central venous catheters. Catheter malposition is likely to precede the development of superior vena cava perforations, a catastrophic complication of central venous catheters. Catheter malposition after initial adequate placement is a very unusual long-term complication and delayed recognition of this complication may have disastrous consequences. Should the catheter change position so the tip is angled toward the sidewall, the repetitive movement of the catheter tip that occurs with respiratory excursion and the cardiac cycle may lead to endothelial injury and eventual erosion of the vein. These problems are thought to be alleviated in the patient receiving long-term intravenous therapy by using a soft Silastic catheter, which may not cause as much damage to the endothelium of the vein. We report three patients with left-sided long-term indwelling Silastic catheters that had changed position over time who presented with chest pain upon infusion of their total parenteral nutrition solutions. In each case, chest x-ray revealed that the tip of the catheter had migrated and was directed against the sidewall of the superior vena cava. In each case, catheter removal and replacement with a new catheter into the right side (subclavian and jugular systems) led to prompt relief of the patient's symptoms.
文献中有多篇报道称,使用临时中心静脉导管会导致无名静脉或上腔静脉出现血管侵蚀。导管位置不当可能先于上腔静脉穿孔的发生,而上腔静脉穿孔是中心静脉导管的一种灾难性并发症。初始放置合适后导管位置发生改变是一种非常罕见的长期并发症,对该并发症的延迟识别可能会产生灾难性后果。如果导管位置改变,致使尖端朝向侧壁,那么随着呼吸运动和心动周期,导管尖端的反复移动可能会导致内皮损伤,最终造成静脉侵蚀。人们认为,对于接受长期静脉治疗的患者,使用柔软的硅橡胶导管可能会缓解这些问题,因为这种导管对静脉内皮的损伤可能较小。我们报告了三例患者,他们长期留置的左侧硅橡胶导管随时间推移发生了位置改变,在输注全胃肠外营养溶液时出现胸痛。在每例患者中,胸部X线检查显示导管尖端已移位并指向了上腔静脉的侧壁。在每例患者中,拔除导管并在右侧(锁骨下和颈内静脉系统)重新置入新导管后,患者症状迅速缓解。