Ikeuchi T, Matsumoto K, Onodera Y, Kai Y, Yoshikawa R, Furuhata A
Department of Urology, Fujigaoka Hospital, School of Medicine, Showa University.
Nihon Hinyokika Gakkai Zasshi. 1994 Jun;85(6):918-24. doi: 10.5980/jpnjurol1989.85.918.
The degree of damage on the peristomal skin of 42 patients who accepted the urostomy was visually and histologically evaluated. The incidence of damages on the areas of the skin where the materials was applied was 85.7%. The occurrence of non-active lesions (mainly permanent pigment change) was statistically more significant than the active lesions (mainly redness) [p < 0.05]. The incidence of skin lesions using the skin barrier agents was significantly lower statistically than the incidence with the adhesive medication indicating a superior treatment for the skin condition [p < 0.05]. Although the gross appearances were normal, the microscopic and electron microscopic evaluations detected chronic damages indicating comparatively evident changes. The results suggest that these histological evaluations are useful in examining the damage on peristomal skin.
对42例接受尿流改道术患者的造口周围皮肤损伤程度进行了肉眼和组织学评估。材料应用部位皮肤损伤的发生率为85.7%。非活动性病变（主要是永久性色素改变）的发生率在统计学上比活动性病变（主要是发红）更显著[p < 0.05]。使用皮肤屏障剂时皮肤病变的发生率在统计学上显著低于使用粘性药物时的发生率，表明对皮肤状况有更好的治疗效果[p < 0.05]。尽管肉眼外观正常，但显微镜和电子显微镜评估检测到慢性损伤，表明有较为明显的变化。结果表明，这些组织学评估有助于检查造口周围皮肤的损伤。
