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[偶然发现的肾细胞癌肿瘤剜除术的临床评估]

[Clinical evaluations of tumor enucleation for incidental renal cell carcinoma].

作者信息

Tsujihata M, Miyake O, Itoh H, Itatani H

机构信息

Department of Urology, Sumitomo Hospital.

出版信息

Nihon Hinyokika Gakkai Zasshi. 1994 Jun;85(6):968-73. doi: 10.5980/jpnjurol1989.85.968.

Abstract

We performed tumor enucleation in 21 patients of renal tumors from Jan. 1980 to Feb. 1993. Of them 19 had renal cell carcinoma. We reviewed the results of clinical experiences. Preoperatively, all patient underwent ultrasound, computerized tomography (CT) and angiography, and evaluated tumor characteristics in terms of its localization, size and pre or absence of pseudocapsule. All cases were shown to be well encapsulated. Of them 17 were asymptomatic and detected incidentally, whereas remaining one case was bilateral renal cell carcinoma clinically characterized by gross hematuria. This case was treated by radical nephrectomy on the right side and enucleation of the tumor on the left side. All cases had localized renal cell carcinoma (stage 1) of low grade (15 cases of grade 1 and 3 of grade 2), and the diameter of the tumor averaged 3.4 cm. Of 18 cases 2 died, one died of causes unrelated to RCC and the other of the metastasis of bilateral RCC after nephrectomy. The 16 cases are presently free of disease for maximal follow up period of 92 months. We consider that tumor enucleation will be indicated for tumors found incidentally, surrounded by pseudocapsule, of small size (less than 3.0 cm in diameter), and of low grade and low stage, and that tumor enucleation for renal cell carcinoma could be curative yet preserve renal function in selected patients.

摘要

1980年1月至1993年2月期间,我们对21例肾肿瘤患者实施了肿瘤剜除术。其中19例为肾细胞癌。我们回顾了临床经验结果。术前,所有患者均接受了超声、计算机断层扫描(CT)和血管造影检查,并根据肿瘤的位置、大小以及有无假包膜来评估肿瘤特征。所有病例均显示有完整包膜。其中17例无症状,为偶然发现,而其余1例为双侧肾细胞癌,临床表现为肉眼血尿。该病例接受了右侧根治性肾切除术和左侧肿瘤剜除术。所有病例均为局限性肾细胞癌(1期),低级别(1级15例,2级3例),肿瘤直径平均为3.4 cm。18例患者中有2例死亡,1例死于与肾细胞癌无关的原因,另1例死于肾切除术后双侧肾细胞癌转移。16例患者目前在最长92个月的随访期内无疾病复发。我们认为,对于偶然发现的、被假包膜包裹、体积小(直径小于3.0 cm)、低级别且低分期的肿瘤,肿瘤剜除术是适用的,并且对于肾细胞癌,肿瘤剜除术在部分患者中可能治愈疾病且保留肾功能。

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