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用于法医毒理学的毛细管气相色谱药物筛查。

Capillary gas chromatographic drug screen for use in forensic toxicology.

作者信息

Drummer O H, Horomidis S, Kourtis S, Syrjanen M L, Tippett P

机构信息

Victorian Institute of Forensic Pathology, Monash University, South Melbourne, Australia.

出版信息

J Anal Toxicol. 1994 May-Jun;18(3):134-8. doi: 10.1093/jat/18.3.134.

Abstract

A screening method is presented involving the use of capillary gas chromatography using a BP-5 column and nitrogen-phosphorous detection. This method is a quick yet reliable procedure for a large range of neutral and basic drugs and uses 1 mL or less of blood. Running standards that contain a number of commonly observed drugs with each batch of cases allows for more accurate tentative identifications of likely drugs in unknown cases and also provides a measure of quality assurance. This method is suitable for postmortem and clinical blood samples as well as plasma and serum.

摘要

本文介绍了一种筛查方法,该方法采用配备BP-5色谱柱的毛细管气相色谱法和氮磷检测法。此方法对于大量中性和碱性药物而言,是一种快速且可靠的程序,并且只需1毫升或更少的血液。每批病例检测时使用包含多种常见药物的运行标准品,有助于更准确地初步鉴定未知病例中可能含有的药物,同时也提供了一种质量保证措施。该方法适用于尸检和临床血液样本以及血浆和血清。

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