用于法医毒理学的毛细管气相色谱药物筛查。
Capillary gas chromatographic drug screen for use in forensic toxicology.
作者信息
Drummer O H, Horomidis S, Kourtis S, Syrjanen M L, Tippett P
机构信息
Victorian Institute of Forensic Pathology, Monash University, South Melbourne, Australia.
出版信息
J Anal Toxicol. 1994 May-Jun;18(3):134-8. doi: 10.1093/jat/18.3.134.
A screening method is presented involving the use of capillary gas chromatography using a BP-5 column and nitrogen-phosphorous detection. This method is a quick yet reliable procedure for a large range of neutral and basic drugs and uses 1 mL or less of blood. Running standards that contain a number of commonly observed drugs with each batch of cases allows for more accurate tentative identifications of likely drugs in unknown cases and also provides a measure of quality assurance. This method is suitable for postmortem and clinical blood samples as well as plasma and serum.
本文介绍了一种筛查方法，该方法采用配备BP-5色谱柱的毛细管气相色谱法和氮磷检测法。此方法对于大量中性和碱性药物而言，是一种快速且可靠的程序，并且只需1毫升或更少的血液。每批病例检测时使用包含多种常见药物的运行标准品，有助于更准确地初步鉴定未知病例中可能含有的药物，同时也提供了一种质量保证措施。该方法适用于尸检和临床血液样本以及血浆和血清。
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