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射频腰椎小关节去神经术:预后因素分析

Radiofrequency lumbar facet denervation: analysis of prognostic factors.

作者信息

North Richard B, Han Misop, Zahurak Marianna, Kidd David H

机构信息

Departments of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA Departments of Biostatistics, The Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.

出版信息

Pain. 1994 Apr;57(1):77-83. doi: 10.1016/0304-3959(94)90110-4.

Abstract

Percutaneous radiofrequency lumbar facet denervation has been in use as a treatment for intractable, mechanical low back pain for over 2 decades. A number of case series have been reported with high rates of success in selected patients; however, there has been limited objective outcome assessment, long-term follow-up, and analysis of prognostic factors. We have reviewed our experience with diagnostic lumbar facet blocks and percutaneous radiofrequency denervation at a mean follow-up interval of 3.2 years. Long-term outcome has been assessed by disinterested third party interview. Of 82 patients selected for these procedures, 56 had undergone prior low back surgery. Following diagnostic medial branch posterior primary ramus blocks, 42 reported at least 50% relief of pain and proceeded to radiofrequency denervation. Forty-five percent of patients undergoing denervation reported at least 50% relief of pain at long-term follow-up. Among the 40 patients who only underwent temporary blocks, 13% reported relief (i.e., spontaneous improvement or placebo effect) by at least 50% at long-term follow-up). By multivariate statistical analysis, patients undergoing bilateral blocks for bilateral or axial symptoms were significantly more likely to achieve temporary relief, and to proceed to permanent denervation. There was no difference, however, between the long-term results of bilateral denervation for bilateral or axial pain and those of unilateral denervation for unilateral pain. There was no significant difference in the rate of response between the 56 patients who had undergone prior lumbosacral spine surgery and the 26 who had not. There were no complications from the procedure.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

经皮射频腰椎小关节去神经术已被用于治疗顽固性机械性下腰痛超过20年。已有多项病例系列报道了部分患者的高成功率;然而,客观结果评估、长期随访及预后因素分析有限。我们回顾了平均随访间隔3.2年的诊断性腰椎小关节阻滞和经皮射频去神经术的经验。长期结果由无利害关系的第三方访谈评估。在接受这些手术的82例患者中,56例曾接受过下腰部手术。在诊断性内侧支后支阻滞之后,42例报告疼痛缓解至少50%并接受了射频去神经术。45%接受去神经术的患者在长期随访中报告疼痛缓解至少50%。在仅接受临时阻滞的40例患者中,13%在长期随访中报告缓解(即自发改善或安慰剂效应)至少50%。通过多变量统计分析,因双侧或轴向症状接受双侧阻滞的患者更有可能获得临时缓解并接受永久性去神经术。然而,双侧或轴向疼痛的双侧去神经术与单侧疼痛的单侧去神经术的长期结果并无差异。曾接受腰骶部脊柱手术的56例患者与未接受手术的26例患者之间的反应率无显著差异。该手术无并发症。(摘要截选至250词)

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