Saunders K B, Fernando S S, Dalton H R, Joseph A
Department of Medicine, St George's Hospital and Medical School, London.
Thorax. 1994 Jul;49(7):725-7. doi: 10.1136/thx.49.7.725.
A 37 year old patient with chronic active hepatitis progressing to cirrhosis presented with increasing breathlessness and was found to be hypoxic with finger clubbing. A progressive exercise study with measurement of oxygen saturation (SaO2) showed abnormally high ventilation and desaturation to 81% at 100 W. Serial studies over nearly two years showed, first, deterioration, then improvement with lower ventilation and higher saturation levels at all work loads. This could not be correlated with any change in treatment with azathioprine, prednisolone, or propranolol.
一名37岁的慢性活动性肝炎进展为肝硬化的患者出现进行性呼吸困难，检查发现存在缺氧及杵状指。一项通过测量血氧饱和度（SaO2）进行的递增运动研究显示，通气异常高，在100瓦时血氧饱和度降至81%。近两年来的系列研究表明，首先是病情恶化，随后有所改善，在所有工作负荷下通气量降低且饱和度升高。这与硫唑嘌呤、泼尼松龙或普萘洛尔治疗的任何变化均无关联。
