Zuskin E, Mustajbegović J, Kanceljak B, Stilinović L
Skola narodnog zdravlja Andrija Stampa Medicinskog fakulteta Sveucilista u Zagrebu.
Arh Hig Rada Toksikol. 1994 Mar;45(1):31-8.
The relationship between respiratory symptoms and immunological reactions was studied in 57 female workers holding jobs in the poultry food processing industry and in 51 non-exposed female workers. The prevalence of all chronic respiratory symptoms was significantly higher in exposed than in control workers (P < 0.01) except for occupational asthma. The prevalence of chronic respiratory symptoms in exposed workers was highest for chronic cough (49.1%), followed by dyspnoea (43.9%), rhinitis (38.6%), chronic phlegm (31.6%) and chronic bronchitis (26.3%). Occupational asthma was found in 5.3% of exposed workers. Exposed workers with positive skin prick test to poultry food demonstrated a higher prevalence of all chronic respiratory symptoms than those with negative skin tests, although the difference was statistically significant only for rhinitis (P < 0.05). The most frequent positive skin reactions were found for poultry food extract (exposed: 66.7%; control: 25.5%; P < 0.05). Increased IgE serum level was found in 19 (33.3%) exposed and in four (7.8%) control workers (P < 0.01). Three exposed workers with occupational asthma demonstrated increased IgE serum level. Our data indicate that occupational exposure to poultry food dust may be associated with the development of chronic respiratory symptoms and immunological changes in exposed workers.
对57名从事家禽食品加工业的女工和51名未接触的女工进行了呼吸症状与免疫反应之间关系的研究。除职业性哮喘外,所有慢性呼吸症状的患病率在接触组均显著高于对照组(P<0.01)。接触组工人慢性呼吸症状的患病率以慢性咳嗽最高(49.1%),其次是呼吸困难(43.9%)、鼻炎(38.6%)、慢性咳痰(31.6%)和慢性支气管炎(26.3%)。在5.3%的接触组工人中发现了职业性哮喘。对家禽食品皮肤点刺试验呈阳性的接触组工人,所有慢性呼吸症状的患病率均高于皮肤试验阴性的工人,尽管仅鼻炎的差异有统计学意义(P<0.05)。家禽食品提取物的皮肤阳性反应最为常见(接触组:66.7%;对照组:25.5%;P<0.05)。19名(33.3%)接触组工人和4名(7.8%)对照组工人血清IgE水平升高(P<0.01)。3名患有职业性哮喘的接触组工人血清IgE水平升高。我们的数据表明,职业性接触家禽食品粉尘可能与接触工人慢性呼吸症状的发生及免疫变化有关。