[1909年韦斯特林描述的雪白丝衣霉菌株所表现出的抗生作用。II. 活性谱]

[Antibiosis shown by a strain of Byssochlamys nivea Westling, 1909. II. Activity spectrum].

作者信息

Percebois G

出版信息

Mycopathologia. 1975 Feb 28;55(1):1-4. doi: 10.1007/BF00467081.

DOI:10.1007/BF00467081

Abstract

A strain of Byssochlamys nivea cultivated in a liquid medium (Saccharose: 50 g: NaNo3: 2 g; KH2PO4: 1 g; KCL: 0.5 g; MgSO4, 7H2O: 0.5 g; water to 1000 ml) produces, at 24 degrees C, an antibiotic substance which appears after several days of growth (10-12 days). Among 43 strains of Bacteria Gram (minus) belonging to 10 genera none was resistant. The most was susceptible, save Pseudomonas aeruginosa, Serratia marcescens, Moraxella glucidolytica. On the the great bulk of the Bacteria (Gram +) tested was little influenced, except certain strains of Bacillus. The filtrate is ineffectual against Mycobacteria and Fungi (yeast or mould) at the concentration used. This substance seemed to be different of those produced by Byssochlamys fluva (byssochlamic acid) and by some species of Paecilomyces (P. varioti, P. persicinus, P. elegans, P. variabilis, P. fusidioides).

摘要

在液体培养基（蔗糖：50克；硝酸钠：2克；磷酸二氢钾：1克；氯化钾：0.5克；硫酸镁·7水合物：0.5克；加水至1000毫升）中培养的雪白丝衣霉菌株，在24摄氏度下培养几天后（10 - 12天）会产生一种抗生素物质。在属于10个属的43株革兰氏阴性菌中，没有一株具有抗性。除铜绿假单胞菌、黏质沙雷氏菌、解糖嗜冷杆菌外，大多数菌株都非常敏感。在所测试的大多数革兰氏阳性菌中，除某些芽孢杆菌菌株外，受影响较小。在所使用的浓度下，滤液对分枝杆菌和真菌（酵母或霉菌）无效。这种物质似乎与雪白丝衣霉产生的物质（丝衣霉酸）以及某些拟青霉属物种（变灰拟青霉、波斯拟青霉、雅致拟青霉、可变拟青霉、梭形拟青霉）产生的物质不同。

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引用本文的文献

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[Common presence on strawberries of ascospores of Byssochlamys nivea capable of producing patulin].

Mycopathologia. 1975 Dec 23;57(2):109-11. doi: 10.1007/BF01365712.

本文引用的文献

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Studies in the biochemistry of micro-organisms: The metabolic products of Byssochlamys fulva Olliver and Smith.微生物生物化学研究：黄丝衣霉（奥利弗和史密斯）的代谢产物

Biochem J. 1933;27(6):1814-9. doi: 10.1042/bj0271814.

2

Studies on variotin, a new antifungal antibiotic. I. Preparations and properties of variotin.关于新型抗真菌抗生素变菌素的研究。一、变菌素的制备与性质

J Antibiot (Tokyo). 1959 Sep;12:195-200.

3

Studies on variotin, a new antifungal antibiotic. II. Taxonomical studies on variotin-producing strain.新型抗真菌抗生素变菌素的研究。II. 产变菌素菌株的分类学研究。

J Antibiot (Tokyo). 1959 Sep;12:201-2.

4

Isolation and characterization of paecilomycerol, a new steroidal antiviral antibiotic. Studies on antiviral and antitumor antibiotics. XXI.新型甾体抗病毒抗生素拟青霉醇的分离与特性研究。抗病毒与抗肿瘤抗生素研究。 XXI

J Antibiot (Tokyo). 1969 Sep;22(9):419-22. doi: 10.7164/antibiotics.22.419.

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