Kato A, Hishida A, Ishibashi R, Nakajima T, Ohura M, Furuya R, Kumagai H, Kimura M, Kaneko E
First Department of Medicine, Hamamatsu University School of Medicine.
Intern Med. 1994 Apr;33(4):231-3. doi: 10.2169/internalmedicine.33.231.
Nephrogenic diabetes insipidus associated with ureteral obstruction is rare. We report a case of nephrogenic diabetes insipidus associated with ureteral obstruction caused by ileal leiomyosarcoma in a 32-year-old man. The treatment with trichlorothiazide and diclofenac sodium reduced urine output from 8 L/day to 4 L/day. Six months after nephrostomy, urine output decreased to 2.5 L/day without any drug administration. This case suggests that ureteral obstruction may cause an increase in urine output to 8 L/day and that surgical treatment for ureteral obstruction is effective in reducing urine output in nephrogenic diabetes insipidus patients with ureteral obstruction.
与输尿管梗阻相关的肾性尿崩症很罕见。我们报告了一例32岁男性因回肠平滑肌肉瘤导致输尿管梗阻而引发肾性尿崩症的病例。用氢氯噻嗪和双氯芬酸钠治疗后，尿量从每天8升降至4升。肾造瘘术后六个月，未使用任何药物尿量就降至每天2.5升。该病例表明，输尿管梗阻可能导致尿量增加至每天8升，并且对于患有输尿管梗阻的肾性尿崩症患者，针对输尿管梗阻的手术治疗在减少尿量方面是有效的。
