Grancai D, Grancaiová Z
Katedra farmakognózie a botaniky Farmaceutickej fakulty Univerzity Komenského, Bratislava.
Ceska Slov Farm. 1994 Jul;43(4):147-54.
Alkaloids represent an important group of therapeutically significant secondary metabolites. The plants of the genus Veratrum contain alkaloids with an antihypertensive effect. Also the genera Schoenocaulon and Zygadenus are sources of veratrum alkaloids. The present paper presents a survey of isolated alkaloids from the underground and aerial parts of 17 species of the genus Veratrum. The alkaloids occur as glycosides, aglycones or in the form of esters with various acids. In conformity with the IUPAC regulations for the nomenclature of steroids, Veratrum alkaloids were divided into 7 groups. The present paper lists the compounds of the first two groups, i.e. (1) alkaloids of the jervanine and veratranine types (I-XXIII), and (2) alkaloids with the cevanine skeleton (XXIV-XXXV). The individual compounds are characterized by their physico-chemical constants (melting point, optical rotation).
生物碱是一类重要的具有治疗意义的次生代谢产物。藜芦属植物含有具有降压作用的生物碱。绿藜芦属和棋盘花属植物也是藜芦生物碱的来源。本文综述了从17种藜芦属植物的地下部分和地上部分分离得到的生物碱。生物碱以糖苷、苷元或与各种酸形成酯的形式存在。根据国际纯粹与应用化学联合会（IUPAC）关于甾体命名的规定，藜芦生物碱分为7组。本文列出了前两组的化合物，即(1)介藜芦胺和藜芦胺型生物碱（I-XXIII），以及(2)具有瑟文骨架的生物碱（XXIV-XXXV）。各化合物通过其物理化学常数（熔点、旋光度）进行表征。
