Ruch J V
Institut de Biologie Médicale, Faculté de Médecine, 11, Strasbourg.
C R Seances Soc Biol Fil. 1993;187(5):575-81.
Several experimental results led to the hypothesis that odontoblast's and ameloblast's genetic programmes may determine a minimal number of cell cycles before overt differentiation can be triggered by specific, epigenetic, matrix-mediated interactions. The cell kinetic dependent maturation of the dental cells could imply transcriptional modifications of matrix molecules and paracrine factors involved in the control of the respective cytodifferentiations and of specific receptors conferring competence to the responding cells.
