Bartos V
Klinika diabetologie a experimentální terapie Institutu klinické a experimentální medicíny, Praha.
Cas Lek Cesk. 1994 Jul 18;133(14):426-8.
Long-term results indicate that diabetics who developed chronic renal failure do better after renal transplantation than during dialyzation treatment. Despite this in diabetics after renal transplantation cardiovascular or cerebrovascular death is relatively frequent. The objective of this retrospective analysis was evaluation of the effect of the period of renal failure before transplantation on the mortality of the recipients.
From a group of 56 diabetics where in 1985-1992 on account of renal failure a transplantation was made 47 patients were selected where valid data on the period of pre-transplantation renal failure could be obtained. In 29 surviving recipients the mean period was 6.4 +/- 5.3 months, while in those who died it was 15.4 +/- 11.6 months (p < 0.001). In nine who died as a result of atherosclerotic complications the pre-transplantation period was 19.5 +/- 11.6 months, in those who died from infectious complications it was 11.3 +/- 10.6 months (the difference is not statistically significant, p > 0.05). Five of 9 patients died from atherosclerotic complications within 6 months after transplantation and as many as 7 from 9 from infectious complications.
The results of a retrospective analysis support the view that renal transplantations in diabetic patients should be made as early as possible.
长期结果表明，患有慢性肾衰竭的糖尿病患者肾移植后的情况比透析治疗期间要好。尽管如此，肾移植后的糖尿病患者心血管或脑血管死亡相对常见。这项回顾性分析的目的是评估移植前肾衰竭时间对受者死亡率的影响。
从1985 - 1992年间因肾衰竭进行移植的56名糖尿病患者中，选取了47名能够获得移植前肾衰竭时间有效数据的患者。在29名存活的受者中，平均时间为6.4±5.3个月，而死亡者的平均时间为15.4±11.6个月（p<0.001）。在9名因动脉粥样硬化并发症死亡的患者中，移植前时间为19.5±11.6个月，因感染并发症死亡者的移植前时间为11.3±10.6个月（差异无统计学意义，p>0.05）。9名患者中有5名在移植后6个月内死于动脉粥样硬化并发症，9名中有7名死于感染并发症。
回顾性分析结果支持以下观点，即糖尿病患者的肾移植应尽早进行。
