Hamperl H
Virchows Arch B Cell Pathol. 1975;18(1):73-81.
Nuclei of the epithelia of the ducts can enter into the tongue- or clublike protrusion, which is characteristic of apocrine secretion. Together with the protrusions the nuclei may be discharged into the lumen, an occurrence one could call apocrine estrusion of nuclei. It can be found up to the sixth decade. II. Occasionally single lobuli show all signs of a fat- (milk-) secretion of fat (milk) and of apocrine estrusion of nuclei, leading to the formation of elements resembling colostrum bodies as they occur in the milk. The cases involved as a rule menstruating women. The secretion, therefore, seems to be due to hormonal influence on especially sensible lobuli of the mastopathic breast.
导管上皮细胞核可进入舌状或棒状突出物,这是顶浆分泌的特征。细胞核可与突出物一起排入管腔,这种情况可称为细胞核的顶浆排出。这种现象在六十岁之前都可发现。二、偶尔单个小叶会出现脂肪(乳汁)分泌和细胞核顶浆排出的所有迹象,导致形成类似初乳小体的成分,就像在乳汁中出现的那样。受累病例通常为育龄女性。因此,这种分泌似乎是由于激素对乳腺病乳房中特别敏感的小叶的影响。