Nahata M C, Schad P A
Colleges of Pharmacy and Medicine, Ohio State University, Columbus 43210.
J Clin Pharm Ther. 1994 Apr;19(2):117-8. doi: 10.1111/j.1365-2710.1994.tb01122.x.
Bronchiolitis is a common viral respiratory infection in infants and young children. The objective of this study was to assess the pattern of drug usage in paediatric patients with bronchiolitis. One hundred patients (aged 2 weeks to 22 months) were evaluated. Of these, 64% had a respiratory syncytial virus infection. The drug therapy included albuterol in 99%, corticosteroids in 36%, aminophylline in 12% and ribavirin in 2% of the patients. The drug doses and frequencies, and durations of therapy varied substantially among patients. This emphasizes the need for well-designed research to develop optimal dosage regimens in paediatric patients with bronchiolitis.
细支气管炎是婴幼儿常见的病毒性呼吸道感染。本研究的目的是评估患细支气管炎的儿科患者的用药模式。对100名患者（年龄2周至22个月）进行了评估。其中，64%的患者感染了呼吸道合胞病毒。药物治疗包括：99%的患者使用了沙丁胺醇，36%的患者使用了皮质类固醇，12%的患者使用了氨茶碱，2%的患者使用了利巴韦林。患者之间的药物剂量、用药频率和治疗持续时间差异很大。这强调了开展精心设计的研究以制定患细支气管炎的儿科患者最佳给药方案的必要性。
