van der Hem L G, van der Linden C J, Ticheler C H, Hoitsma A J, Corstens F H
Department of Surgery, University Hospital St. Radboud, Nijmegen, The Netherlands.
J Nucl Med. 1994 Sep;35(9):1488-90.
We present two cases of compromised pancreatic graft perfusion on a routine 99mTc-HMPAO-scan. The radiopharmaceutical, hexamethylpropyleneamine oxime (HMPAO), labeled with 99mTc-provided high-quality scintigraphic images of transplanted pancreatic grafts. Findings were compared with subsequently performed x-ray digital subtraction angiographs. Pathological examination of both resected grafts revealed venous thrombosis in one case and graft pancreatitis in the other case of disturbed graft perfusion on a 99mTc-HMPAO-scan. While 99mTc-HMPAO scans of pancreatic grafts are not specific for early thrombosis, they seem to be a helpful tool in diagnosing pancreatic dysfunction in general, necessitating further diagnostic steps to elucidate the specific cause.
我们展示了两例在常规99mTc-HMPAO扫描中胰腺移植灌注受损的病例。用99mTc标记的放射性药物六甲基丙烯胺肟（HMPAO）提供了移植胰腺的高质量闪烁图像。将结果与随后进行的X线数字减影血管造影进行比较。对两个切除的移植物进行病理检查，发现一例为静脉血栓形成，另一例在99mTc-HMPAO扫描中移植物灌注紊乱的病例为移植物胰腺炎。虽然胰腺移植物的99mTc-HMPAO扫描对早期血栓形成不具有特异性，但它们似乎是诊断一般胰腺功能障碍的有用工具，需要进一步的诊断步骤来阐明具体原因。
